Publications

Peer-review journals

Afratis N, Karamanou K, Piperigkou Z, Vynios D.H and Theocharis A.D. The role of heparins and nano-heparins as therapeutic tools in breast cancer. Glycoconj J. 34:299-307. 2016. doi: 10.1007/s10719-016-9742-7.

Piperigkou Z, Karamanou K, Afratis N, Bouris P, Gialeli C, Belmiro S, Pavao M, Vynios D.H, Tsatsakis A. Biochemical and toxicological evaluation of nanoheparins in cell function properties, proteasome activation and expression of key matrix molecules. Toxicol Lett. 240:32-42. 2015. doi: 10.1016/j.toxlet.2015.10.005.

Heidari-Hamedani G, Vivès RR, Seffouh A, Afratis NA, Oosterhof A, van Kuppevelt TH, Karamanos NK, Metintas M, Hjerpe A, Dobra K, Szatmári T. Syndecan-1 alters heparan sulfate composition and signaling pathways in malignant mesothelioma. Cell Signal. 27:2054-67. 2015. doi: 10.1016/j.cellsig.2015.07.017.

Theocharis AD, Skandalis SS, Neill T, Multhaupt HA, Hubo M, Frey H, Gopal S, Gomes A, Afratis N, Lim HC, Couchman JR, Filmus J, Ralph D S, Schaefer L, Iozzo RV, Karamanos NK. Ιnsights into the key roles of proteoglycans in breast cancer biology and translational medicine. Biochim Biophys Acta. 1855:276-300. 2015. doi: 10.1016/j.bbcan.2015.03.006.

Bouris P, Skandalis SS, Piperigkou Z, Afratis N, Karamanou K, Aletras AJ, Moustakas A, Theocharis AD, Karamanos NK. Estrogen receptor alpha mediates epithelial to mesenchymal transition, expression of specific matrix effectors and functional properties of breast cancer cells. Matrix Biol. 43:42-60. 2015. doi: 10.1016/j.matbio.2015.02.008.

Asimakopoulou AP, Malavaki C, Afratis NA, Theocharis AD, Lamari FN, Karamanos NK. Validated capillary electrophoretic assays for disaccharide composition analysis of galactosaminoglycans in biologic samples and drugs/nutraceuticals. Methods Mol Biol. 1229:129-41. 2015. doi: 10.1007/978-1-4939-1714-3_13.

Book Chapter

Afratis NA, Sagi I. Novel Approaches for Extracellular Matrix Targeting in Disease Treatment. Methods in Molecular Biology, 2019.

Asimakopoulou AP, Malavaki C, Afratis NA, Theocharis AD, Lamari FN, Karamanos NK. Validated capillary electrophoretic assays for disaccharide composition analysis of galactosaminoglycans in biologic samples and drugs/nutraceuticals. Methods in Molecular Biology, 2015.

Skandalis SS, Gialeli C, Afratis N, Aletras A. J, Tsegenidis T, Theocharis AD, Karamanos NK. Pharmacological targeting of proteoglycans and metalloproteinases: an emerging aspect in cancer treatment. Extracellular Matrix: Pathobiology and Signaling, DeGruyter, 2012